SignUpFreshman Organic Chemistry
Yale,, Fall 2008 , Prof. J. Michael McBride
Updated On 02 Feb, 19
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Yale,, Fall 2008 , Prof. J. Michael McBride
Updated On 02 Feb, 19
How Do You Know - Force Laws, Lewis Structures and Resonance - Double Minima, Earnshaws Theorem and Plum - Puddings - Coping with Smallness and Scanning Probe Microscopy - X-Ray Diffraction-Seeing Bonds by Electron Difference Density - Quantum Mechanical Kinetic Energy - One-Dimensional Wave Functions - Chladni Figures and One - Electron Atoms - Reality and the Orbital Approximation - Orbital Correction and Plum - Pudding Molecules - Overlap and Atom - Pair Bonds - Overlap and Energy - Match - Checking Hybridization Theory with XH_3-Chemical Reactivity: SOMO, HOMO, and LUMO - Recognizing Functional Groups - Reaction Analogies and Carbonyl Reactivity - Amide, Carboxylic Acid and Alkyl Lithium-Oxygen and the Chemical Revolution - Rise of the Atomic Theory - Berzelius to Liebig and W�hler - Radical and Type Theories (1832-1850)-Valence Theory and Constitutional Structure (1858) - Determining Chemical Structure by Isomer Counting (1869)
Models in 3D Space (1869-1877); Optical Isomers - Vant Hoffs Tetrahedral Carbon and ChiralityCommunicating Molecular Structure in Diagrams and Words - Stereochemical Nomenclature; Racemization and Resolution - Preparing Single Enantiomers and the Mechanism of Optical Rotation - Esomeprazole as an Example of Drug Testing and Usage - Preparing Single Enantiomers and Conformational Energy - Stereotopicity and Baeyer Strain Theory -Conformational Energy and Molecular Mechanics - Sharpless Oxidation Catalysts and the Conformation of Cycloalkanes - Understanding Molecular Structure and Energy through Standard Bonds - Bond Energies, the Boltzmann Factor and Entropy - Potential Energy Surfaces, Transition State Theory and Reaction Mechanism
4.1 ( 11 )
Freshman Organic Chemistry (CHEM 125)
After discussing the statistical basis of the law of mass action, the lecture turns to developing a framework for understanding reaction rates. A potential energy surface that associates energy with polyatomic geometry can be realized physically for a linear, triatomic system, but it is more practical to use collective energies for starting material, transition state, and product, together with Eyring theory, to predict rates. Free-radical chain halogenation provides examples of predicting reaction equilibria and rates from bond dissociation energies. The lecture concludes with a summary of the semesters topics from the perspective of physical-organic chemistry.
0000 - Chapter 1. The Boltzmann Factor and Entropy Against Traditional Views on Society
0740 - Chapter 2. The Statistical Basis of the Law of Mass Action
1313 - Chapter 3. Understanding Reaction Rates The Potential Energy Surface and Collective Energies
2940 - Chapter 4. Free Radical Halogenations Predicting Reaction Equilibria and Rates
4301 - Chapter 5. A Summary of the First Semester
Complete course materials are available at the Open Yale Courses website httpopen.yale.educourses
This course was recorded in Fall 2008.
Sam
Sep 12, 2018
Excellent course helped me understand topic that i couldn't while attendinfg my college.
Dembe
March 29, 2019
Great course. Thank you very much.
