IIT Madras, , Prof. Mukesh Doble
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Updated On 02 Feb, 19
Introduction and course contents - Bioprocess case studies/flow sheet - Characteristics of biomolecules and their differences - Various down stream process steps - Fundamental principles of obtaining the product from cell cultures intracellular vs. extracellular product - Cell disruption mechanical, enzymatic, and chemical methods - Pre-treatment strategies - Solid-liquid separation filtration and centrifugation
Adsorption - Liquid-liquid extraction - Membrane separation ultrafiltration and reverse osmosis, dialysis etc - Precipitation of proteins by different methods - Chromatograph principles, instruments and practice - Crystallization - Distillation - Drying - lyophilization - Stabilization of bioproducts - Utilities (Air, water, steam etc)
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Downstream Processing by Prof. Mukesh Doble, Department of Biotechnology, IIT Madras. For more details on NPTEL visit httpnptel.iitm.ac.in
Sep 12, 2018
Excellent course helped me understand topic that i couldn't while attendinfg my college.
March 29, 2019
Great course. Thank you very much.